Meet Truly O2

We are a Colorado company founded by scientists.

With elevations over a mile (or two!) above sea level, over 300 days of sunshine, desert dryness, and big seasonal swings in temperature, we know the challenges your skin faces every day.

Truly O2 founder family

Straightforward Skincare.

Limited ingredient formulations that make skincare easy.

We are founded on the premise that our micro-oxygen formulas harness the powerful effects of oxygen for your skin and simplifies your skincare routine. Truly O2 starts with a nine-ingredient base formulation, enriched with oxygen, made vegan and cruelty-free.

We do not use additives that may harm healthy skin, including fragrances, color additives, parabens, phthalates, propylene glycol, formaldehyde, sodium lauryl sulfate (SLS), mineral oil, petrolatum, paraffin, diethanolamine (DEA), polyethylene beads, or animal products.

Safe Science.

Designed by scientists for maximum efficacy.

Our oxygen technology has been developed with support from research programs with the National Science Foundation and National Institutes of Health.

While researching oxygen treatments for lung disease and wound healing, our founders learned that skin health and wellness can be greatly improved by oxygen and lipid formulations. Our research and development programs are dedicated to simple, pure oxygen delivery in formulations to be applied directly to the skin.

Our History:


Lipid-Oxygen Microspheres are created by scientists at Columbia University.


The National Science Foundation awards a research grant to the University of Colorado for the use of microspheres in intravenous blood oxygenation.

Oxygen Microspheres are studied for oncology, targeted drug delivery, ultrasound contrast and echocardiography. Micro-sphere research programs are established at the University of Colorado, Boulder.


Future Truly O2 Director of R&D, Paul Mountford, begins work on his PhD program in the Microsphere technology lab at the University of Colorado, Boulder.


The US Air Force initiates studies of Oxygen Microspheres for survival of severe lung injury, with researchers at the University of Nebraska and the University of Colorado, Boulder.


Company research begins on treatment of wound healing and Hyperbaric Oxygen Therapy, leading to breakthroughs in skincare and demonstrating potential benefits of Topical Oxygen Therapy in treating skin conditions.


Truly O2 is formed to develop and commercialize topical oxygen skincare treatments.

Under the direction of Dr. Mountford, the original formulation of Oxygen Microsphere skincare is introduced to a test panel and focus group in Boulder, Colorado. The company files patent applications for Lipid-oxygen Microsphere skincare.


Dr. Mountford’s mother, who has a chronic skin condition requiring dermatology treatment, is the first patient treated with Truly O2 Micro-oxygen Moisturizer and sees clinical improvement with Truly O2 Micro-oxygen Moisturizer, using the product under the care and direction of her Dermatologist.

Oxygen-infused skin moisturizers are furthered in development – (original) Micro-Oxygen Moisturizer, Micro-Oxygen Hydrating Night Cream, Oil-Free Micro-Oxygen Moisturizer and Micro-Oxygen Body Lotion formulations are released. Clinical benefits and improved aesthetic outcomes are observed in facial procedures.


Truly O2 is introduced as an over-the-counter solution to reach skincare consumers, aesthetic practice patients and customers that will realize the benefit of oxygen in management of skin conditions. Micro-oxygen Hand and Foot Salve is developed and launched.


Truly O2 Professional is launched with multiple oxygen-enriched skincare products in development for use by skincare professionals. Truly O2 continues procurement of novel, oxygen-enriched products to estheticians, dermatologists, and facial plastic-surgeons, working to reduce post-ablative procedure trauma, inflammation, and redness, improve treatment outcomes, and promote overall skin health and wellness.

Micro-Oxygen Recovery Foam is introduced to select aesthetic and dermatology practices. Positive results are observed in post-procedure recovery time and patient satisfaction.

Oxygen For Your Skin.

Get the pure oxygen you won't find anywhere else and say hello to beautiful, hydrated skin.